Artificial intelligence (AI) is currently one of the most controversial and discussed topic and the first question that is raised every time is “will it be helpful or not for a human being?”. Several types of AI will increasingly be applied in the healthcare domain due to the complexity and rise of data in this field. Machine learning, an important subset of AI, provides a way to make the healthcare system more dynamic and robust. This article presents some applications of machine learning in the healthcare domain. It also provides the role of Internet of Things (IoT) systems through vital signs monitoring for elderly patients and it highlights the impact of machine learning in diagnosis management, treatment prediction or reducing errors with the help of remote health monitoring.?